Call community condition Qualified licensing board or state-managed substances authority for information on how to circumvent and detect abuse or diversion of the product.
Steer clear of offering acetaminophen and codeine phosphate tablets to small children amongst twelve to 18 yrs of age who've possibility elements for respiration challenges including obstructive snooze apnea, weight problems, or fundamental lung problems.
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Get professional medical assistance without delay for those who discover any of the following: slow/shallow respiration, extreme drowsiness/trouble waking up, confusion.
Hyperalgesia and Allodynia: Scenarios of hyperalgesia and allodynia have already been claimed with opioid therapy of any duration (see WARNINGS).
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Reserve concomitant prescribing of those medicines for use in individuals for whom substitute procedure choices are insufficient. Restrict dosages and durations to the bare minimum needed. Inform people and caregivers of this possible conversation, educate them on the signs and more info symptoms of respiratory despair (like sedation).
Codeine sulfate check here was not mutagenic during the in vitro bacterial reverse mutation more info assay or clastogenic from the in vitro Chinese hamster here ovary cell chromosome aberration assay.
To reduce the potential risk of respiratory melancholy, proper dosing and titration of acetaminophen and codeine phosphate tablets are necessary (see DOSAGE AND ADMINISTRATION).
All this has led to what's identified as Medication-Assisted Cure, which can be a lot more economical and much easier to obtain when compared to the normal clinical product. As well as, it could possibly provide a for much longer listing of sufferers.
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Respiratory despair can occur Anytime through opioid therapy, especially when initiating and pursuing dosage raises with acetaminophen and codeine phosphate tablets. Look at this chance when selecting an First dose and when earning dose adjustments (see WARNINGS).
Notify patients never to consider acetaminophen and codeine phosphate tablets though making use of any prescription drugs that inhibit monoamine oxidase. Sufferers should not start off MAOIs though getting acetaminophen and codeine phosphate tablets (see PRECAUTIONS, Drug Interactions).
Get healthcare aid instantly Should you have any incredibly major side effects, website including: fainting, seizure.